1,25 Million Euro for neurovascular research at the Goethe University Frankfurt receives Prof. Acker-Palmer from the prestigious Reinhart Koselleck grant. In her project, she aims to investigate the hidden functions of vascular-neuronal interfaces. Blood vessels not only transport oxygen and nutrients, they are also sites of communicative processes that regulate brain development and maintain its function.
Endothelial cells — the cells that form the inner lining of all vessels — exchange signals with nerve cells and glial cells. This is crucial for shaping brain circuits and the formation of brain architecture. Disrupted exchange can lead to developmental disorders as well as neurodegeneration.
With state-of-the-art imaging, the creation of molecular profiles, and genetic models, she aims to uncover where and how endothelial cells interact with neurons and other brain cells and how these contacts influence the brain's connectivity and structure.
Reinhart Koselleck projects are awarded to "researchers distinguished by outstanding scientific achievements." Approval requires particularly innovative approaches and a certain degree of risk.
October, 2025
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