We had a fantastic day at the 1st Science Festival Frankfurt of the Goethe University Frankfurt hosted by the Frankfurt Alliance!! Together with our partner booth from the Max Planck Institute für Heart and Lung Research we showed fascinating insights into our heart and lung research 💝 The highlight of our booth was a walkable heart model funded by the Kassel-Stiftung.
On the main stage Prof. Stefanie Dimmeler was invited to join the panel discussion on the topic "Basic research" in which she explained the importance of basic research for medical progress.
It was a pleasure to be part of this event!
28. September 2024
Excited 3rd to 6th graders filled the lecture hall at the Goethe-Universität Frankfurt Westend Campus last wednesday, eager to learn. CPI researcher Guillermo Luxàn brought science to life, when he interactively explained the biology of Heart and Lung ❤ 🌬 Their enthusiasm and curiosity made the event truly special!
25. September 2024
Lung cancer remains the leading cause of cancer-related deaths in the U.S. and Europe. Despite available treatments, more than 70% of patients experience relapse and eventually succumb to the disease, often due to its spread to other parts of the body. While targeted therapies offer some hope, they benefit only a small percentage of patients, and resistance to these treatments is a common issue. Many patients rely on chemotherapy and radiation, but these approaches often fail, leading to aggressive cancer progression. Although immune therapies show promise, they are limited by their success rates and potential side effects. Early detection and a deeper understanding of lung cancer’s underlying mechanisms are essential for improving prevention and treatment outcomes.
An official research statement from the American Thoracic Society (ATS), co-chaired by Prof. Dr. Rajkumar Savai, DZL-PI and scientific coordinator of the DZL Lung Cancer Disease Area, alongside Prof. Seyed Javad Moghaddam from MD Anderson and Prof. Robert L. Keith from the University of Colorado Denver School of Medicine, addresses the urgent need for further research into lung cancer. The statement, titled “Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non–Small Cell Lung Cancer,” was developed by an international, multidisciplinary team of basic, translational, and clinical scientists who carefully reviewed existing data to refine research questions aimed at understanding the transformation of premalignant lung lesions into advanced lung cancer.
The statement identifies significant gaps in current knowledge and proposes critical research questions designed to expand our understanding of the mechanisms behind the progression of premalignant lung lesions to full-blown cancer. The goal is to explore innovative strategies to intercept lung cancer at its earliest stages.
The report underscores the urgent need to prioritize research on the biological mechanisms of premalignant progression in the lung. It also highlights the ongoing challenges in screening, detection, and early intervention, emphasizing the importance of focused investigations. Such efforts are essential to developing effective preventive strategies that could ultimately reduce lung cancer incidence and improve patient outcomes.
Prof. Rajkumar Savai is a leading figure in lung cancer research, serving as a professor at the Institute for Lung Research (ILH) at Justus Liebig University in Giessen. He leads the research group "Lung Microenvironmental Niche in Cancerogenesis" and heads the Oncology Basic Research Unit at Medical Clinic V of the University Hospital Giessen and Marburg. Additionally, he is a group leader at the Department of Lung Development and Remodeling at the Max Planck Institute for Heart and Lung Research (MPI-HLR) in Bad Nauheim. His research primarily focuses on unraveling the mechanisms of lung cancer development and progression, with a particular emphasis on the tumor microenvironment.
Original publication: Moghaddam SJ, Savai R, Salehi-Rad R, Sengupta S, Kammer MN, Massion P, Beane JE, Ostrin EJ, Priolo C, Tennis MA, Stabile LP, Bauer AK, Sears CR, Szabo E, Rivera MP, Powell CA, Kadara H, Jenkins BJ, Dubinett SM, Houghton AM, Kim CF, Keith RL. Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non-Small Cell Lung Cancer. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2024 Aug 8. doi: 10.1164/rccm.202406-1168ST. Epub ahead of print. PMID: 39115548.
https://pubmed.ncbi.nlm.nih.gov/39115548/
We look forward to share our research at the annual Science Day of the Deparment of Medicine at the Justus-Liebig-University in Gießen. The Science Day will be held Friday 22th November 2024 at the Med. Lehrzentrum Seltersberg (MLZ), Klinikstraße 29 from 9:30 to 15:00.
Doctoral candidates, students, research assistants and professors, as well as early career scientists of the JLU are welcomed to present their research.
Abstracts can be submitted until September 9, 2024.
Find more information here:
Deutsche Herzstiftung appoints Prof. Dr. med. Samuel T. Sossalla to Scientific Advisory Board where he will support the patient organization committee.
Prof. Sossalla is a leading clinician in cardiology, serving as the head of the Cardiology Department at the Heart Center of the Kerckhoff Clinic in Bad Nauheim and as the director of Medical Clinic I at the University Hospital Gießen (UKGM).
Find the full article here:
October 16, 2024
University Hospital Frankfurt, Building 22
The symposium will bring together scientists from different disciplines in the Rhein-Main area to discuss state-of-the-art approaches for the integration of multi-modal data sources (e.g. image, genome, clinical data) for predictive medicine tasks (e.g. survival prediction, disease sub types). In addition to the lectures on the main topics listed below, this symposium will also feature a poster session and a lecture by keynote speaker Prof. Dr. Ivan Costa from the RWTH Aachen University.
Oral/poster presentations will be selected from submitted abstracts.
Registration closed.
Excited to announce that we had an incredible retreat! We thank everyone for presenting their research and engaging discussions!
We’re grateful for our valuable research collaboration with the Tongji Medial College of the Huazhong University of Science and Technology in Wuhan, China.
In April we welcomed Zhijie Li to the institute for vascular signaling of Prof. Dr. Ingrid Fleming. Zhijie is working on his master´s thesis about soluble epoxide hydrolase (sEH), a crucial lipid metabolizing enzyme in cardiopulmonary diseases. Together with his German colleagues, he explores innovative treatments and techniques.
Stay tuned for updates on our groundbreaking projects!
